Thrombophilia
References

1. Severe VTE in a young Man with Klinefelter’s Syndrome and Heterozygosis for both G20210 Prothrombin and Factor V Leiden Mutations: Lapecorella M, Marino R, De Pergola G, Scaraggi FA, Speciale V, De Mitrio V (2003) Blood Coagulation Fibrinolysis.

2. Klinefelter’s Syndrome and VTE: Copyright (2003) Lippincott Williams & Wilkins PMID: 12544736 [PubMed - indexed for MEDLINE]

3. Klinefelter’s Syndrome associated with mixed connective tissue disease (Sharp’s Syndrome) and Thrombophilia and Postthrombotic Syndrome - Kasten R, Pfirrmann G, Voigtlander V (2005).J Dtsch Dermatol Ges.3(8),623-6.

4. DVT: by Alexander G.G. Turpie, MD. "Deep Venous Thrombosis - The Merck's Manuals Online Medical Library

5. Overview of the Causes of Thrombophilia: UpToDate.com, K.A. Bauer, G.Y.Lip, L.K.Leung, S.A.Landaw Version 17.3 (July 2009).

6. Activated protein C resistance and factor V Leiden: UpToDate.com, K.A. Bauer, G.Y.Lip, L.K.Leung, S.A.Landaw (May 2009).

7. Prothrombin gene mutation: UpToDate.com, K.A. Bauer, G.Y.Lip, L.K.Leung, S.A.Landaw (July 2009).

8. Mateo, J, Oliver, A, Borrell, M, et al. Laboratory evaluation and clinical characteristics of 2,132 consecutive unselected patients with venous thromboembolism — results of the Spanish Multicentric Study on Thrombophilia (EMET-Study). Thromb Haemost 1997; 77:444.

9. Margaglione, M, Brancaccio, V, Giuliani, N, et al. Increased risk for venous thrombosis in carriers of the prothrombin G A20210 gene variant. Ann Intern Med 1998; 129:89.

10. Heit JA (2007). "Thrombophilia: common questions on laboratory assessment and management". Hematology Am Soc Hematol Educ Program 2007: 127–35. doi:10.1182/asheducation-2007.1.127. PMID 18024620

11. Diagnosis and Treatment of Deep Venous Thrombosis and Pulmonary Embolism, Johns Hopkins Research Study, (2003) NCBI.NLM.NIH.GOV AHRQ Publication No. 03-E016 ISBN: 1-58763-079-6, ISSN: 1530-4396

12. Melinda M. Manore of Oregon State University's Department of Nutrition and Exercise Sciences, http://www.supplementschat.org/homocysteine-b-vitamins-and-heart-disease.html

13. Mazzolai L, Duchosal MA. Hereditary thrombophilia and venous thromboembolism: critical evaluation of the clinical implications of screening.Eur J Vasc Endovasc Surg. 2007; 34 (4) 483-488

14. Family History, In Addition To Genetic and Environmental Risk Factors, Predicts Risk of Deep Vein Thrombosis Source

15. Silverstein MD, Heit JA, Mohr DN, et al. Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study. Arch Intern Med. 1998; 158: 585–593.